Policosanol may increase the blood-thinning effects of aspirin, warfarin (Coumadin) and clopidogrel (Plavix).
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Randomized trial of high loading dose of clopidogrel for reduction of periprocedural myocardial infarction in patients undergoing coronary intervention: results from the ARMYDA-2 (Antiplatelet therapy for Reduction of Myocardial Damage during Angioplasty) study.
Pharmacogenomics of adverse drug reactions: practical applications and perspectives.
Because clopidogrel keeps your blood from clotting, it can also make it easier for you to bleed, even from a minor injury.
Disparity in the reported frequency of aspirin resistance reflects the diverse nature of the populations studied, the wide variety of tests used, and the arbitrary cut-off values imposed ().
In support of the multivariate analysis, a trend of a higher risk of bleeding with increasing doses of aspirin is observed consistently in patients undergoing PCI, CABG, or no revascularization.
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For patients with ST-elevation myocardial infarction (STEMI), clopidogrel bisulfate has been shown to reduce the rate of death from any cause and the rate of a combined endpoint of death, re-infarction, or stroke.
Although in normal subjects no interaction with theophylline or propranolol was found, there have been clinical reports of interaction with other drugs metabolized via the cytochrome P450 system (e.
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Percutaneous Coronary Intervention and Concomitant Antithrombotic Therapy.
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How Recent Data Have Impacted the Treatment of Internal Carotid Artery Stenosis.
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The results for the efficacy analyses for these studies are described below.
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Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control; 2010.
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Its potential is further limited by poor correlation of the results of available test systems such as collagen-induced aggregometry and the platelet-function analyzer PFA-100 for measuring the response to aspirin ( Figure 1 Platelet Aggregation in Blood Samples as Tested with the Platelet-Function Analyzer PFA-100 and Light-Transmission Aggregometry.
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PCI, the relative benefit of bivalirudin with respect to ischemic and bleeding events was maintained regardless of renal function.
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For this strain of rat no similar tumor has been noted historically, but a finding involving only one tumor is difficult to interpret.
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